![]() Also, remember primary diseases are diseases that originate within the gland in question (e.g., primary hyperthyroidism is due to a defect in the thyroid gland), and secondary diseases represent change in one organ as a result of disease in another organ (e.g., secondary hyperthyroidism may be due to a TSH-secreting pituitary adenoma). If the patient has a TSH-secreting pituitary adenoma, T 4 and T 3 levels as well as the TSH will be high normally, high T 3 and T 4 levels should cause a low TSH level. Parathyroid Glands: Parathyroid glands are located behind the thyroid glands, which increases the blood calcium level in the body. ![]() Adrenal glands control the behaviour in emotional situations. T 3 and T 4 then cause feedback inhibition of pituitary release of TSH. Adrenal Glands: Adrenal glands are the glands that produce several hormones and steroids in the body like adrenaline, aldosterone, cortisol, etc. For example, thyroid-releasing hormone (TRH) released by the hypothalamus stimulates thyroid-stimulating hormone (TSH) production by the pituitary gland, which in turn stimulates triiodothyronine (T 3) and thyroxine (T 4) production by the thyroid gland. ![]() A working knowledge of the pathways that regulate normal hormone levels helps to interpret the laboratory values in patients being worked up for suspected endocrine disorders. ![]()
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